The Bears struggled against Justin Jefferson the first time around, and they might have a rough go of it again potentially down two of their top three cornerbacks Sunday.
Beast or not, DeAndre Hopkins might have some trouble against James Bradberry, especially as defenses increasingly catch on to Arizona's static route combinations.
After a two-week lull, Jamison Crowder might see his target volume spike upward against a Dolphins defense that's better outside than in the slot.
It's been a disappointing season for Marquise Brown and the Ravens offense, but Brown might not see an easier matchup all year than the Titans defense.
The red-hot Keenan Allen has to slow down eventually, but with weak slot coverage and competent boundary coverage the Dolphins might funnel another healthy workload toward him in Week 10.
Rarely does a receiver have as good of an on-paper matchup as Terry McLaurin against the hapless yet uptempo Cowboys -- both efficiency and volume appear close to ideal.
Preston Williams broke out in Week 5 and might keep it rolling in Week 6 against the Jets, whose strong slot coverage encourages offenses to target their weak outside corners.
It's been a disheartening season for the Giants offense, but they might get on track as Darius Slayton and company take on a struggling Dallas secondary.
With nicked up and aging corners set to face off against him, D.J. Moore is in a bounce-back spot against the uptempo Cardinals.
No matter whether he runs more from the slot or out wide, it's difficult to see what the Raiders corners can do to slow down D.J. Moore.